Fig. 3
Abundant DAI is readily apparent 6 h following cFPI in the micro pig thalamus. Representative photomicrographs of APP immunofluorescence in the thalamus of animals sustaining sham (a) or cFPI (b). While sham-injured animals had little to no APP labeling, prevalent APP+ axonal swellings, indicative of DAI, were apparent following injury. c Bar graph depicting the average number of APP labeled axonal swellings/ 0.72 mm2 of thalamic tissue. Graph depicts mean ± standard error of the mean. *p < 0.05. Scale bar: 50 μm