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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig

Fig. 6

Microglia activation occurs in thalamic sectors sustaining acute DAI 6 h following mTBI. Representative confocal micrographs of APP (red; a and d) and Iba-1 (green; b and e), with overlays in c and f, in the thalamus of the same injured animal. Interestingly, areas lacking axonal injury (ac) appear to contain inactive ramified microglia (arrows), whereas thalamic sites exhibiting DAI, indicated by accumulation of APP in axonal swellings (df), also appear to contain the majority of morphologically activated Iba-1+ microglia (arrow heads). Scale bar: 20 μm

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