Fig. 1
From: Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE
Hypoxia resulted in increased capillary density. Spinal cord sections of mice exposed to 10 % hypoxia for 3 weeks and normoxic controls were prepared as detailed in the “Materials and methods” section. Glut-1+ microvessels were counted in 20–30 fields per sample from normoxia- (a) and hypoxia- (b) exposed mice. The bar graphs (c) are the mean ± SD number of vessels per field. Glut-1+ microvessels were also more in MOG-immunized hypoxia-exposed spinal cords (e), when compared to normoxic MOG-immunized spinal cords (d). Quantification of those microvessels was presented as bar graph (f) (mean ± SD of at least three mice per group). Significant differences between the groups are denoted with asterisks (*** p < 0.001)