Fig. 10

Effects of BBG on ICH-induced gp91^phox expression in the striatum. Gp91^phox significantly colocalized with Iba-1 (a). Most gp91^phox signals overlapped with iNOS (b). Western blot (c, d) and immunofluorescence labeling (e) showing that BBG treatment significantly reduced the striatal gp91^phox expression 24 h after ICH compared with the Vehicle group. n = 4 (d) or n = 6 (e) rats per group. Scale bar = 20 μm (a) or 25 μm (b) or 50 μm (e). Data represent means ± SD. ^* P < 0.05; ^** P < 0.01. BBG brilliant blue G, GAPDH glyceraldehyde 3-phosphate dehydrogenase, ICH intracerebral hemorrhage, iNOS inducible nitric oxide synthase