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Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

Fig. 11

Effects of BBG on ICH-induced 3-NT expression in the striatum. 3-NT significantly colocalized with Iba-1 (a). Most 3-NT signals overlapped with gp91phox (b). Western blot (c, d) and immunofluorescence staining (e) showing that BBG treatment significantly suppressed striatal 3-NT expression 24 h after ICH compared with the Vehicle group. n = 4 (a, b, e) or n = 6 (c, d) rats per group. Bar = 12.5 μm (a, b) or 50 μm (e). Data represent means ± SD. * P < 0.05, ** P < 0.01. BBG brilliant blue G, GAPDH glyceraldehyde 3-phosphate dehydrogenase, ICH intracerebral hemorrhage, 3-NT 3-nitrotyrosine

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