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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite

Fig. 2

Expression profiles of NLRP3, ASC, and caspase-1 p20 subunit after ICH. Western blot analysis (a) for the time course expressions of NLRP3 (b), ASC (c), and caspase-1 p20 subunit (d) in the ipsilateral hemisphere of Sham and ICH rats within 72 h. Quantification of NLRP3, ASC, and caspase-1 p20 subunit expression is shown, respectively, n = 4 rats per group and time point. Data represent means ± SD. * P < 0.05 vs. Sham, ** P < 0.01 vs. Sham. ASC adaptor protein apoptosis-associated speck-like protein containing a CARD, GAPDH glyceraldehyde 3-phosphate dehydrogenase, ICH intracerebral hemorrhage, NLRP3 pyrin domain-containing 3

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Journal of Neuroinflammation

ISSN: 1742-2094