Fig. 5

Western blot analysis and IHC of MPO in the brain cortex of rats 24 h after SAH. MPO protein levels increased after SAH and significantly decreased following r-PGRN treatment (a). IHC revealed that MPO-positive cells decreased after treatment with PGRN, which significantly increased after SAH (b). There was no difference between the untreated SAH group and the PBS-treated SAH group. Data are expressed as the mean ± SEM from six rats. ***p < 0.001 and **p < 0.01 compared with the sham group, ^ns p > 0.05 compared with the SAH group, ^## p < 0.01 and ^# p < 0.05 compared with the SAH group