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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated

Fig. 4

Anti-rrNF IgG2b isotype-specific response is genetically regulated. a LOD plot for QTL linkage analysis using Haley-Knott regression on OD values for anti-rrNF IgG2b antibodies at day 35 p.i. in 174 female DA backcross rats. b Allelic effect plot at the peak marker of QTL linked in the female DA backcross population. Threshold indicated by the black line for 95 % significant linkage is 2.6, and LOD score is 3.3. p value given in the allelic effect plot was calculated using non-parametric Mann-Whitney test in GraphPad Prism 5.0

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Journal of Neuroinflammation

ISSN: 1742-2094