Fig. 5From: MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulatedAnti-rrNF IgG and IgG1 isotype-specific and IgG2b isotype-specific reactivity in 333 DA backcross rats. Anti-rrNF IgG and IgG1 isotype-specific and IgG2b isotype-specific levels were assessed in serum at day 35 after MOG immunization in the 333 DA backcross by ELISA, of which 136 rats were healthy and 197 were sick. Sera were diluted in 1:200. Data are presented in arbitrary units (AU). The statistical significance between the healthy and sick rats was calculated by using non-parametric Mann-Whitney test in GraphPad Prism 5.0. ***p < 0.001; ****p < 0.0001. The line represents the mean valueBack to article page