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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

Fig. 3

Overview of results from miRNA expression profiling in whole blood. a Venn diagram showing the overlap of all miRNAs detected in serum and whole blood after removal of duplicated mature miRNAs. b Venn diagram showing the overlap of miRNAs found to be deregulated in serum and whole blood (raw p values <0.05) in the three-group comparison of patients with NMOSD, CIS/RRMS, and healthy controls by ANOVA. c The absolute expression levels of the two most significantly deregulated whole blood miRNAs, has-miR-1180-3p and has-miR-424-3p, in the three-group comparison (ANOVA) of patients with NMOSD, CIS/RRMS, and healthy controls are shown as boxplots. CIS clinically isolated syndrome, RRMS relapsing-remitting multiple sclerosis, NMOSD neuromyelitis optica spectrum disorder, ANOVA analysis of variance

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