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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms

Fig. 4

Phosphorylation of p38 is increased in hippocampus of PCS rats and is normalized by treatment with sildenafil. a, b Representative images of phosphorylated p38 (P-p38) in the CA1 region of the dorsal hippocampus in control and PCS rats, treated with vehicle or sildenafil (SIL). a Phosphorylated p38 immunostained with DAB. Note the higher intensity in PCS rats. b Confocal images of the immunostaining for Neun (green) and phosphorylated p38 (red) in neurons of the CA1 region. Scale bar 100 μm in (a) and 20 μm in (b)

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