Fig. 7From: Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanismsSpatial learning in the Morris water maze is impaired in PCS rats and is restored by treatment with sildenafil. Spatial learning ability in the Morris water maze was assessed in sham and PCS rats, treated with vehicle or sildenafil (SIL). a Escape latencies (in seconds) to reach the platform during the different sessions. b Escape latencies (in seconds) in the third session. Values are the mean ± SEM of 15–18 rats per group. Values significantly different from control rats are indicated by asterisks and from PCS rats by a. *p < 0.05; a p < 0.05; aa p < 0.01Back to article page