Fig. 2
From: Altered morphological dynamics of activated microglia after induction of status epilepticus
Activated microglia scan larger territory, without changing their velocity. a Maximal intensity projection of time-lapse two-photon images at different time points during spontaneous movements of microglial processes in control (left column) and 48 h after induction of SE (right column). The figure shows retracting (red symbols) and elongating processes (green symbols), with the starting/arriving points marked by circles. Scale bar, 5 μm. b Cumulative probability of all elongation movements by single process tips measured in control (black) and KA-injected (red) animals shows no difference between the two groups (p = 0.99, KS test). c Cumulative probability of territory explored by all single process tips measured in control (black) and KA-injected (red) animals. p = 0.019, KS test. d Relationship between the median of explored territory by microglial processes versus the median of the cell body size in each experiment. The red line represents the linear fit (r = 0.8)