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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice

Fig. 6

IgG deposition is reduced in the cortex and hippocampus of MRL/+ → MRL/lpr chimeric mice. Immunofluorescent staining, quantitated in (a) absolute values of mean intensity, demonstrated significantly increased tissue penetration and deposition of IgG in MRL/lpr → MRL/lpr mice as compared to MLR/+ → MRL/+ and MRL/+ → MRL/lpr mice in both the cortex and the hippocampus. Representative images taken with a ×20 objective are shown in (b). Error bars = SEM, *p < 0.05, **p < 0.01, ****p < 0.0001

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