Fig. 5
Stroke induced changes in immune and inflammatory cell subsets in the spleen are affected by the expression of IFN-β. In parallel to PBMCs, we isolated splenocytes. a Percentages of CD11b+ and b MHCII+ (activated) CD11b+ cells within splenocytes. c Percentage of NK and d NKT cells within splenocytes. e Percentages of B220+ (immature) and f B220+MHCII+ (mature and activated) B cells in the spleen. g Ratio of splenic CD3+CD4+ Th and CD3+CD8+ TC cells based on the FCT analysis (WT, n = 6–7, IFN-βKO, n = 7–8). *p < 0.05, **p < 0.01, and **p < 0.001 (Bonferroni correction)