Parameter | Time point | Sham | Sham | tMCAo | tMCAo |
---|---|---|---|---|---|
WT | IFN-βKO | WT | IFN-βKO | ||
Temperature (°C) | 24 h | 36.9 ± 0.4 | 36.5 ± 0.6 | 36.1 ± 0.4* | 36.3 ± 0.6 |
2 days | 37.6 ± 0.1 | 38.0 ± 1.2 | 36.7 ± 0.9 | 36.3 ± 1.2 | |
3 days | 37.9 ± 0.5 | 38.1 ± 1.2 | 37.4 ± 0.3 | 37.2 ± 0.6 | |
7 days | 38.2 ± 0.2 | 38.3 ± 0.3 | 37.4 ± 1.0 | 37.5 ± 1.2 | |
Weight loss (% baseline) | 24 h | 8.9 ± 0.8 | 8.1 ± 4.2 | 10.0 ± 2.2 | 10.2 ± 2.1 |
2 days | 9.4 ± 2.0 | 6.3 ± 4.7 | 13.6 ± 5.2 | 14.7 ± 3.0** | |
3 daysa | 6.8 ± 2.6 | 5.4 ± 4.2 | 15.0 ± 5.5 | 16.9 ± 3.3* | |
7 days | 8.9 ± 2.8 | 5.0 ± 5.0 | 11.2 ± 8.6 | 16.2 ± 11.7 |