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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis

Fig. 3

Glibenclamide and Abcc8−/− reduce disease severity in EAE. a Mean values of clinical scores following EAE induction for untreated WT/EAE mice, for glibenclamide-treated WT/EAE mice and Abcc8−/−/EAE mice; glibenclamide treatment was started on pid-10, when >20 % of mice had clinical scores of 1 or greater; 10 mice/group. b Daily serum glucose for first 4 days in mice receiving no treatment (empty circle) or glibenclamide treatment (empty diamonds)

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Journal of Neuroinflammation

ISSN: 1742-2094