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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

Fig. 2

Effects of LPS on body weight, brain weight, and BBB permeability. Panel a shows that all doses of LPS had a significant effect on body weight (n = 6/group). Panel b shows no dose of LPS had an effect on brain weight (n = 6/group). Panel c shows that BBB permeability was increased to 14C-sucrose 24 but not 4 h after 3 mg/kg of LPS (n = 3–4/group). Panel d shows that 3 mg/kg LPS increased BBB permeability to albumin (n = 3/group). *p < 0.05; ***p < 0.001

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