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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Epistasis analysis links immune cascades and cerebral amyloidosis

Fig. 1

Interaction between C9 and IL6r genes. a Representation of the SNP rs261752 (C9 gene) in chromosome 5 and SNP rs7514452 (IL6r gene) in chromosome 1. b C9 × IL6r (rs7514452) on amyloid deposition. The interaction between C9 and IL6r genes is associated with amyloid burden. Error bars represent the standard error. Small numbers represent the subsample size for each genotype combination. *The mean SUVR for the assigned genotypes are different between each other (p = 0.05 (two-tailed)). **The mean SUVR for this genotype is higher than all other genotypes (p values ≤ 0.05 (two-tailed)). p values are adjusted according to Tukey’s HSD test. c Representation of the SNP rs261752 (C9 gene) in chromosome 5 and SNP rs4240872 (IL6r gene) in chromosome 1. d C9 × IL6r (rs4240872) on amyloid deposition. The interaction between C9 and IL6r genes is associated with amyloid burden. Error bars represent the standard error. Small numbers represent the subsample size for each genotype combination. *The mean SUVR for the assigned genotypes are different between each other (p = 0.04 (two-tailed)). **The mean SUVR for the genotype CC(C9)*CC(IL6r) is higher than all other assigned genotypes (p values ≤0.05 (two-tailed)). p values are adjusted according to Tukey’s HSD test

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