Low serum ficolin-3 levels are associated with severity and poor outcome in traumatic brain injury

Table 3 Analysis and comparison of area under receiver operating characteristic curve

Variables	1-week mortality prediction		6-month mortality prediction		6-month functional outcome prediction
Variables	AUC (95 % CI)	P value	AUC (95 % CI)	P value	AUC (95 % CI)	P value
GCS scores	0.883 (0.814–0.933)	Ref.	0.875 (0.805–0.927)	Ref.	0.872 (0.802–0.925)	Ref.
Ficolin-3 levels	0.836 (0.760–0.896)	0.305	0.818 (0.740–0.881)	0.186	0.815 (0.736–0.878)	0.196
GCS scores + ficolin-3 levels	0.915 (0.853–0.957)	0.294	0.904 (0.839–0.949)	0.232	0.900 (0.835–0.946)	0.207

A combined logistic-regression model was configured to estimate the additive benefit of ficolin-3 to GCS score. Comparisons of AUCs were performed using z test. GCS score + ficolin-3 level indicates the combined use of GCS score and ficolin-3 level to predict prognosis
AUC area under curve, CI confidence interval, GCS Glasgow Coma Scale, Ref. reference

ISSN: 1742-2094