Table 2 Summary of alterations in IgG1 glycosylation related to the compartment (CSF vs. serum, see also Fig. 3) and the disease (MS vs. control CSF, Fig. 4a–d, g)
From: Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid
Control CSF vs. control serum | MS CSF vs. control CSF | Peak after relapse | |
|---|---|---|---|
Afucosylation | ↑ | ↓ | y |
Bisecting GlcNAc | n.s. | ↑ | y |
Galactosylation | ↓ | ↓ | n |