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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis

Fig. 1

Pro-inflammatory mediator levels in the supernatants and lysates of rhesus macaque frontal cortex sections cultured ex vivo. IL-6 (a), CXCL8 (b), and CCL2 (c) levels were determined by multiplex ELISA in brain tissues that were exposed to B. burgdorferi (Bb), medium alone (Med), B. burgdorferi plus NK1R antagonist (Bb + A), or medium alone plus antagonist (Med + A). The figure shows the arithmetic means ± standard deviations of experimental replicates for each individual animal. **p < 0.001, ***p < 0.0001, ns not significant

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