Fig. 4

Open-field test. Three days after PBS/LPS injection, an open-field test was performed. The graphs represent a distance moved during the test, b percentage of time spent in the border zone of the arena, c percentage of time spent grooming, and d percentage of time spent rearing. There was a significant main effect for group (PBS/LPS) on the distance moved during the test (a; p = 0.0361), percentage of time spent grooming (b; p = 0.0334), and percentage of time spent rearing (d; p = 0.0159). In addition, a significant main effect for treatment (sham/ECS) was found for the percentage of time spent in the border zone (b; p = 0.005). Other main effects did not reach significance, and interaction effects were not significant for any of these parameters