Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease

Fig. 1

Hypoestoxide reduces neuroinflammation in a mouse model of PD. Immunohistochemical analysis of Iba-1 and GFAP in neocortex of non-tg and α-syn-tg mice injected with either vehicle or hypoestoxide. a Immunoreactivity against Iba-1 was analyzed in neocortex of the brains. b, c The numbers of Iba-1-positive cells (b) and the average numbers of branches per Iba-1-positive cell (c) (n = 5 per each group; two-way ANOVA, Bonferroni’s multiple comparison post-test; ***p < 0.001). Error bars represent ±SEM. d Immunoreactivity against GFAP was analyzed in neocortex of the brains. e, f Optical density analysis of GFAP immunoreactivity (e) and the average numbers of branches per GFAP-positive cell (f) (n = 5 per each group; two-way ANOVA, Bonferroni’s multiple comparison post-test; *p < 0.05, **p < 0.01, ***p < 0.001). Error bars represent ±SEM. Scale bars = 100 μm (low magnification) and 20 μm (high magnification)

Back to article page