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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins

Fig. 1

Dorsal root ganglia pathology. a DRG with mild focal satellitosis, which is defined as increased numbers of cells around a neuronal cell body (arrow). b DRG with moderate inflammation that has replaced a few ganglion cells (arrow) with an increase in satellite cells (c) DRG with inflammation associated with a degenerate ganglion cell (arrow). Note the cells encroaching around the outside of the ganglion indicative of neuronophagia, a precursor lesion to the development of a Nageotte nodule. d DRG with a Nageotte nodule, focal proliferation of satellite cells that completely replace foci of neuronal cell loss (arrow)

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Journal of Neuroinflammation

ISSN: 1742-2094