Fig. 2From: Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteinsCorrelates of plasma markers of monocyte activation and monocyte chemoattractants. sCD14 (a–c), sCD163 (d–f), RANTES (g–i), MCP-1 (j–l), and sCD137 (m–o) were measured in plasma at multiple time points throughout infection. a, d, g, j, and m Pre-infection and necropsy plasma concentrations were compared using a Wilcoxon matched-pairs signed-rank test. Necropsy plasma concentrations were grouped according to the lumbar DRG pathology and compared using a Kruskal-Wallis test. The number of BrdU+ monocytes in blood (b, e, h, k, n) and the percent of CD14+ CD16+ monocytes of the total monocyte population (c, f, i, l, o) was determined by flow cytometry and correlated to the plasma soluble protein concentrations at matched time points. A Spearman correlation test was used for all correlations. p value of <0.05 was considered significantBack to article page