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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins

Fig. 5

RANTES, MCP-1, and sCD137 protein levels in DRG tissue. RANTES (a), MCP-1 (b), and sCD137 (c) were detected by Luminex multiplex assay in DRG tissue lysate. Differences in protein concentrations in SIV– and SIV+ DRG tissue were analyzed using a Mann-Whitney test. SIV+ DRGs were grouped according to the tissue pathology. Differences between SIV+ tissue pathology groups were analyzed using a Kruskal-Wallis test, followed by a Dunn’s post-test. The amount of RANTES (d), MCP-1 (e), and sCD137 (f) in DRG tissue lysate were correlated to the number of MAC387+ cells/mm2 determined by immunohistochemistry using a Spearman correlation test. p value of <0.05 was considered significant

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Journal of Neuroinflammation

ISSN: 1742-2094