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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation

Fig. 2

FTY720 treatment decreases effector T cell function. a Expression of IFNG and GZMB in in vitro activated T cells from healthy individuals in the presence or absence of FTY720 as determined by nanostring (n = 6). b Expression of IFNG and GZMB in in vitro activated T cells from healthy individuals in the presence or absence of FTY720 as determined by qPCR (n = 6). c Expression of IFN-γ and GZMB in in vitro activated T cells from healthy individuals in the presence or absence of FTY720 as determined by Luminex-based assay (n = 6). d Expression of IFN-γ and GZMB in in vitro activated T cells from healthy individuals in the presence or absence of FTY720 using flow cytometry (n = 6). *p < 0.05, **p < 0.01, paired non-parametric t tests

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