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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

Fig. 5

ISG15 and PKR protein expression in the spinal cord of mock- and TMEV-infected C57BL/6 mice. a Few cells express ISG15 proteins in TMEV-infected SJL/J mice at 98 dpi. b Many endothelial cells, astrocytes, and neurons express ISG15 proteins in TMEV-infected C57BL/6 mice at 98 dpi. c Low expression of PKR proteins in TMEV-infected SJL/J mice at 98 dpi. d High expression of PKR proteins in oligodendrocytes, microglia/macrophages, and neurons of TMEV-infected C57BL/6 mice at 98 dpi. Immunohistochemistry visualized by the avidin-biotin-peroxidase complex method with 3,3-diaminobenzidine as substrate and counterstaining with Mayer’s hematoxylin. Bar 100 μm

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Journal of Neuroinflammation

ISSN: 1742-2094