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Table 2 Spearman’s rank correlation coefficients between ISG15, PKR, OAS1, Mx1, and Mx2 gene expression with TMEV RNA, inflammation, T cells, B cells, microglia/macrophages, and demyelination in the spinal cord of SJL/J mice

From: Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

ISG mRNA

TMEV RNA

Inflammation (HE)

T cells (CD3)

B cells (CD45R)

Microglia/ Macrophage (MAC3)

Demyelination (LFB)

ISG15

0.809

0.832

0.793

0.714

0.796

0.660

PKR

0.831

0.797

0.798

0.709

0.788

0.638

OAS1

0.816

0.839

0.775

0.736

0.808

0.688

Mx1

0.708

0.762

0.645

0.681

0.775

0.585

Mx2

0.755

0.746

0.663

0.763

0.748

0.632

  1. Significant correlations are marked in italics (P ≤ 0.05)