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Table 2 Spearman’s rank correlation coefficients between ISG15, PKR, OAS1, Mx1, and Mx2 gene expression with TMEV RNA, inflammation, T cells, B cells, microglia/macrophages, and demyelination in the spinal cord of SJL/J mice

From: Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

ISG mRNA TMEV RNA Inflammation (HE) T cells (CD3) B cells (CD45R) Microglia/ Macrophage (MAC3) Demyelination (LFB)
ISG15 0.809 0.832 0.793 0.714 0.796 0.660
PKR 0.831 0.797 0.798 0.709 0.788 0.638
OAS1 0.816 0.839 0.775 0.736 0.808 0.688
Mx1 0.708 0.762 0.645 0.681 0.775 0.585
Mx2 0.755 0.746 0.663 0.763 0.748 0.632
  1. Significant correlations are marked in italics (P ≤ 0.05)