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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

Fig. 2

Complement inhibition reduces microglia/macrophage activation and astrogliosis following MCAO and 7 days reperfusion. a Representative images of activated microglia/macrophages as assessed by Iba-1 immunohistochemical detection across the different groups. Scale bar = 200 μm. b Quantification of Iba-1 immunohistochemical staining. Mean +/− SEM (positive cells per square millimeter), n = 6–8 mice. *p < 0.05, **p < 0.01. c Quantification of reactive astrocytes as assessed by GFAP immunohistochemical detection. Mean +/− SEM (positive cells per square millimeter), n = 5–7 mice. *p < 0.05

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