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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

Fig. 4

CR2-fH increases subventricular zone neuronal proliferation and neuroblast presence at 7 days post-MCAO. a Doublecortin (Dcx+) neuroblasts within the ipsilateral SVZ at 7 days post-MCAO. Bar = Mean, n = 5–7. b Ki-67+ proliferating cells within the ipsilateral subventricular zone (SVZ) of the lateral ventricles. Bar = Mean. c, the subgranular zone (SGZ) of the dentate gyrus. Bar = Mean (density calculated from five random HPF), n = 3–7. *p < 0.05. d Representative images of immunostained sections, ×20 magnification. Scale bar = 150 μm. e Representative immunofluorescence double staining of SVG in CR2-fH-treated mice with anti-BrdU (green) and anti-Dcx (red), showing co-localization of signal

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