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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Modeling leukocyte trafficking at the human blood-nerve barrier in vitro and in vivo geared towards targeted molecular therapies for peripheral neuroinflammation

Fig. 2

Flow-dependent in vitro blood-nerve barrier model. This illustration depicts a set-up for the flow-dependent in vitro blood-nerve barrier model system that allows direct visualization of human leukocyte trafficking at the BNB in real time using time-lapse video microscopy. Leukocytes are infused at physiologically relevant flow rates and leukocyte-endothelial interactions captured by sequential digital photomicrographs that are merged into videos and analyzed under different experimental conditions. Black arrows depict the direction of leukocyte flow

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Journal of Neuroinflammation

ISSN: 1742-2094