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Table 1 Prevalence of CRPS-like signs (allodynia, unweighting, warmth, and edema) observed at 4 weeks and 16 weeks post fracture in fracture rats. The arbitrary criteria indicate approximately 30-50 % normalization of each measurement.

From: Acute versus chronic phase mechanisms in a rat model of CRPS

Signs

Allodynia

Unweighting

Warmth

Edema

Criteria

R-L difference

2R/(R + L) × 100 %

R-L difference

R-L difference

Diagnostic threshold: 5-g reduction

Diagnostic threshold: 30 % reduction

Diagnostic threshold: 1 °C increase

Diagnostic threshold: 0.5-mm increase

FX- 4 WK

90 %

(42/47)

87 %

(33/38)

94 %

(44/47)

73 %

(32/44)

FX- 16 WK

72 %

(34/47)

2 %

(1/47)

19 %

(9/47)

0 %

(0/47)

  1. R right hindpaw, L left hindpaw, FX- 4 WK 4 weeks after fracture, FX- 16 WK 16 weeks after fracture