TY - JOUR AU - Selkoe, D. J. PY - 2001 DA - 2001// TI - Alzheimer’s disease: genes, proteins, and therapy JO - Physiol Rev VL - 81 ID - Selkoe2001 ER - TY - JOUR AU - McGeer, P. L. AU - McGeer, E. G. PY - 2013 DA - 2013// TI - The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy JO - Acta Neuropathol VL - 126 UR - https://doi.org/10.1007/s00401-013-1177-7 DO - 10.1007/s00401-013-1177-7 ID - McGeer2013 ER - TY - JOUR AU - Salminen, A. AU - Ojala, J. AU - Kauppinen, A. AU - Kaarniranta, K. AU - Suuronen, T. PY - 2009 DA - 2009// TI - Inflammation in Alzheimer’s disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors JO - Prog Neurobiol VL - 87 UR - https://doi.org/10.1016/j.pneurobio.2009.01.001 DO - 10.1016/j.pneurobio.2009.01.001 ID - Salminen2009 ER - TY - JOUR AU - Akiyama, H. AU - Arai, T. AU - Kondo, H. AU - Tanno, E. AU - Haga, C. AU - Ikeda, K. PY - 2000 DA - 2000// TI - Cell mediators of inflammation in the Alzheimer disease brain JO - Alzheimer Dis Assoc Disord. VL - 14 UR - https://doi.org/10.1097/00002093-200000001-00008 DO - 10.1097/00002093-200000001-00008 ID - Akiyama2000 ER - TY - JOUR AU - Heneka, M. T. AU - O’Banion, M. K. AU - Terwel, D. AU - Kummer, M. P. PY - 2010 DA - 2010// TI - Neuroinflammatory processes in Alzheimer’s disease JO - J Neural Transm VL - 117 UR - https://doi.org/10.1007/s00702-010-0438-z DO - 10.1007/s00702-010-0438-z ID - Heneka2010 ER - TY - JOUR AU - Lee, Y. J. AU - Han, S. B. AU - Nam, S. Y. AU - Oh, K. W. AU - Hong, J. T. PY - 2010 DA - 2010// TI - Inflammation and Alzheimer’s disease JO - Arch Pharm Res VL - 33 UR - https://doi.org/10.1007/s12272-010-1006-7 DO - 10.1007/s12272-010-1006-7 ID - Lee2010 ER - TY - JOUR AU - Halle, A. AU - Hornung, V. AU - Petzold, G. C. AU - Stewart, C. R. AU - Monks, B. G. AU - Reinheckel, T. PY - 2008 DA - 2008// TI - The NALP3 inflammasome is involved in the innate immune response to amyloid-beta JO - Nat Immunol VL - 9 UR - https://doi.org/10.1038/ni.1636 DO - 10.1038/ni.1636 ID - Halle2008 ER - TY - JOUR AU - Hunter, J. M. AU - Kwan, J. AU - Malek-Ahmadi, M. AU - Maarouf, C. L. AU - Kokjohn, T. A. AU - Belden, C. PY - 2012 DA - 2012// TI - Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer’s disease JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0036893 DO - 10.1371/journal.pone.0036893 ID - Hunter2012 ER - TY - JOUR AU - Reilly, J. F. AU - Games, D. AU - Rydel, R. E. AU - Freedman, S. AU - Schenk, D. AU - Young, W. G. PY - 2003 DA - 2003// TI - Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model JO - Proc Natl Acad Sci U S A VL - 100 UR - https://doi.org/10.1073/pnas.0330745100 DO - 10.1073/pnas.0330745100 ID - Reilly2003 ER - TY - JOUR AU - Shaftel, S. S. AU - Griffin, W. S. AU - O’Banion, M. K. PY - 2008 DA - 2008// TI - The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective JO - J Neuroinflammation. VL - 5 UR - https://doi.org/10.1186/1742-2094-5-7 DO - 10.1186/1742-2094-5-7 ID - Shaftel2008 ER - TY - JOUR AU - McGeer, P. L. AU - McGeer, E. G. PY - 2001 DA - 2001// TI - Inflammation, autotoxicity and Alzheimer disease JO - Neurobiol Aging VL - 22 UR - https://doi.org/10.1016/S0197-4580(01)00289-5 DO - 10.1016/S0197-4580(01)00289-5 ID - McGeer2001 ER - TY - JOUR AU - Rothwell, N. J. AU - Luheshi, G. N. PY - 2000 DA - 2000// TI - Interleukin 1 in the brain: biology, pathology and therapeutic target JO - Trends Neurosci VL - 23 UR - https://doi.org/10.1016/S0166-2236(00)01661-1 DO - 10.1016/S0166-2236(00)01661-1 ID - Rothwell2000 ER - TY - JOUR AU - Dinarello, C. A. PY - 2007 DA - 2007// TI - A signal for the caspase-1 inflammasome free of TLR JO - Immunity VL - 26 UR - https://doi.org/10.1016/j.immuni.2007.04.005 DO - 10.1016/j.immuni.2007.04.005 ID - Dinarello2007 ER - TY - JOUR AU - Yu, H. B. AU - Finlay, B. B. PY - 2008 DA - 2008// TI - The caspase-1 inflammasome: a pilot of innate immune responses JO - Cell Host Microbe VL - 4 UR - https://doi.org/10.1016/j.chom.2008.08.007 DO - 10.1016/j.chom.2008.08.007 ID - Yu2008 ER - TY - JOUR AU - Virgilio, F. PY - 2013 DA - 2013// TI - The therapeutic potential of modifying inflammasomes and NOD-like receptors JO - Pharmacol Rev VL - 65 UR - https://doi.org/10.1124/pr.112.006171 DO - 10.1124/pr.112.006171 ID - Virgilio2013 ER - TY - JOUR AU - Heneka, M. T. AU - Kummer, M. P. AU - Stutz, A. AU - Delekate, A. AU - Schwartz, S. AU - Vieira-Saecker, A. PY - 2013 DA - 2013// TI - NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice JO - Nature VL - 493 UR - https://doi.org/10.1038/nature11729 DO - 10.1038/nature11729 ID - Heneka2013 ER - TY - JOUR AU - Liu, L. AU - Chan, C. PY - 2014 DA - 2014// TI - IPAF inflammasome is involved in interleukin-1beta production from astrocytes, induced by palmitate; implications for Alzheimer’s Disease JO - Neurobiol Aging VL - 35 UR - https://doi.org/10.1016/j.neurobiolaging.2013.08.016 DO - 10.1016/j.neurobiolaging.2013.08.016 ID - Liu2014 ER - TY - JOUR AU - Mariathasan, S. AU - Newton, K. AU - Monack, D. M. AU - Vucic, D. AU - French, D. M. AU - Lee, W. P. PY - 2004 DA - 2004// TI - Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf JO - Nature VL - 430 UR - https://doi.org/10.1038/nature02664 DO - 10.1038/nature02664 ID - Mariathasan2004 ER - TY - JOUR AU - Oakley, H. AU - Cole, S. L. AU - Logan, S. AU - Maus, E. AU - Shao, P. AU - Craft, J. PY - 2006 DA - 2006// TI - Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque formation JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.1202-06.2006 DO - 10.1523/JNEUROSCI.1202-06.2006 ID - Oakley2006 ER - TY - JOUR AU - Couturier, J. AU - Paccalin, M. AU - Morel, M. AU - Terro, F. AU - Milin, S. AU - Pontcharraud, R. PY - 2011 DA - 2011// TI - Prevention of the beta-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures JO - J Neuroinflammation. VL - 8 UR - https://doi.org/10.1186/1742-2094-8-72 DO - 10.1186/1742-2094-8-72 ID - Couturier2011 ER - TY - JOUR AU - Stancu, I. C. AU - Ris, L. AU - Vasconcelos, B. AU - Marinangeli, C. AU - Goeminne, L. AU - Laporte, V. PY - 2014 DA - 2014// TI - Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer’s disease JO - FASEB J VL - 28 UR - https://doi.org/10.1096/fj.13-246702 DO - 10.1096/fj.13-246702 ID - Stancu2014 ER - TY - JOUR AU - Dong, Y. AU - Benveniste, E. N. PY - 2001 DA - 2001// TI - Immune function of astrocytes JO - Glia VL - 36 UR - https://doi.org/10.1002/glia.1107 DO - 10.1002/glia.1107 ID - Dong2001 ER - TY - JOUR AU - Eder, C. PY - 2009 DA - 2009// TI - Mechanisms of interleukin-1beta release JO - Immunobiology VL - 214 UR - https://doi.org/10.1016/j.imbio.2008.11.007 DO - 10.1016/j.imbio.2008.11.007 ID - Eder2009 ER - TY - JOUR AU - Parajuli, B. AU - Sonobe, Y. AU - Horiuchi, H. AU - Takeuchi, H. AU - Mizuno, T. AU - Suzumura, A. PY - 2013 DA - 2013// TI - Oligomeric amyloid beta induces IL-1beta processing via production of ROS: implication in Alzheimer’s disease JO - Cell Death Dis. VL - 4 UR - https://doi.org/10.1038/cddis.2013.503 DO - 10.1038/cddis.2013.503 ID - Parajuli2013 ER - TY - JOUR AU - Jones, R. S. AU - Minogue, A. M. AU - Connor, T. J. AU - Lynch, M. A. PY - 2013 DA - 2013// TI - Amyloid-beta-induced astrocytic phagocytosis is mediated by CD36, CD47 and RAGE JO - J Neuroimmune Pharmacol VL - 8 UR - https://doi.org/10.1007/s11481-012-9427-3 DO - 10.1007/s11481-012-9427-3 ID - Jones2013 ER - TY - JOUR AU - Wyss-Coray, T. AU - Loike, J. D. AU - Brionne, T. C. AU - Lu, E. AU - Anankov, R. AU - Yan, F. PY - 2003 DA - 2003// TI - Adult mouse astrocytes degrade amyloid-beta in vitro and in situ JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm838 DO - 10.1038/nm838 ID - Wyss-Coray2003 ER - TY - JOUR AU - Andjelkovic, A. V. AU - Kerkovich, D. AU - Shanley, J. AU - Pulliam, L. AU - Pachter, J. S. PY - 1999 DA - 1999// TI - Expression of binding sites for beta chemokines on human astrocytes JO - Glia VL - 28 UR - https://doi.org/3.0.CO;2-6 DO - 3.0.CO;2-6 ID - Andjelkovic1999 ER - TY - JOUR AU - Han, Y. AU - Wang, J. AU - Zhou, Z. AU - Ransohoff, R. M. PY - 2000 DA - 2000// TI - TGFbeta1 selectively up-regulates CCR1 expression in primary murine astrocytes JO - Glia VL - 30 UR - https://doi.org/3.0.CO;2-Q DO - 3.0.CO;2-Q ID - Han2000 ER - TY - JOUR AU - Dorf, M. E. AU - Berman, M. A. AU - Tanabe, S. AU - Heesen, M. AU - Luo, Y. PY - 2000 DA - 2000// TI - Astrocytes express functional chemokine receptors JO - J Neuroimmunol VL - 111 UR - https://doi.org/10.1016/S0165-5728(00)00371-4 DO - 10.1016/S0165-5728(00)00371-4 ID - Dorf2000 ER - TY - JOUR AU - Gallagher, M. AU - Burwell, R. AU - Burchinal, M. PY - 1993 DA - 1993// TI - Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze JO - Behav Neurosci VL - 107 UR - https://doi.org/10.1037/0735-7044.107.4.618 DO - 10.1037/0735-7044.107.4.618 ID - Gallagher1993 ER - TY - JOUR AU - Maei, H. R. AU - Zaslavsky, K. AU - Teixeira, C. M. AU - Frankland, P. W. PY - 2009 DA - 2009// TI - What is the most sensitive measure of water maze probe test performance? JO - Front Integr Neurosci. VL - 3 ID - Maei2009 ER - TY - JOUR AU - Schroder, K. AU - Tschopp, J. PY - 2010 DA - 2010// TI - The inflammasomes JO - Cell VL - 140 UR - https://doi.org/10.1016/j.cell.2010.01.040 DO - 10.1016/j.cell.2010.01.040 ID - Schroder2010 ER - TY - JOUR AU - Lamkanfi, M. AU - Dixit, V. M. PY - 2012 DA - 2012// TI - Inflammasomes and their roles in health and disease JO - Annu Rev Cell Dev Biol. VL - 28 UR - https://doi.org/10.1146/annurev-cellbio-101011-155745 DO - 10.1146/annurev-cellbio-101011-155745 ID - Lamkanfi2012 ER - TY - JOUR AU - Walsh, J. G. AU - Muruve, D. A. AU - Power, C. PY - 2014 DA - 2014// TI - Inflammasomes in the CNS JO - Nat Rev Neurosci VL - 15 UR - https://doi.org/10.1038/nrn3638 DO - 10.1038/nrn3638 ID - Walsh2014 ER - TY - JOUR AU - Allan, S. M. AU - Tyrrell, P. J. AU - Rothwell, N. J. PY - 2005 DA - 2005// TI - Interleukin-1 and neuronal injury JO - Nat Rev Immunol VL - 5 UR - https://doi.org/10.1038/nri1664 DO - 10.1038/nri1664 ID - Allan2005 ER - TY - JOUR AU - John, G. R. AU - Lee, S. C. AU - Song, X. AU - Rivieccio, M. AU - Brosnan, C. F. PY - 2005 DA - 2005// TI - IL-1-regulated responses in astrocytes: relevance to injury and recovery JO - Glia VL - 49 UR - https://doi.org/10.1002/glia.20109 DO - 10.1002/glia.20109 ID - John2005 ER - TY - JOUR AU - Gustin, A. AU - Kirchmeyer, M. AU - Koncina, E. AU - Felten, P. AU - Losciuto, S. AU - Heurtaux, T. PY - 2015 DA - 2015// TI - NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0130624 DO - 10.1371/journal.pone.0130624 ID - Gustin2015 ER - TY - JOUR AU - Johann, S. AU - Heitzer, M. AU - Kanagaratnam, M. AU - Goswami, A. AU - Rizo, T. AU - Weis, J. PY - 2015 DA - 2015// TI - NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients JO - Glia ID - Johann2015 ER - TY - JOUR AU - Murphy, N. AU - Grehan, B. AU - Lynch, M. A. PY - 2014 DA - 2014// TI - Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10 JO - Neuromolecular Med VL - 16 UR - https://doi.org/10.1007/s12017-013-8274-6 DO - 10.1007/s12017-013-8274-6 ID - Murphy2014 ER - TY - JOUR AU - Sokolowski, J. D. AU - Mandell, J. W. PY - 2011 DA - 2011// TI - Phagocytic clearance in neurodegeneration JO - Am J Pathol VL - 178 UR - https://doi.org/10.1016/j.ajpath.2010.12.051 DO - 10.1016/j.ajpath.2010.12.051 ID - Sokolowski2011 ER - TY - JOUR AU - Pihlaja, R. AU - Koistinaho, J. AU - Malm, T. AU - Sikkila, H. AU - Vainio, S. AU - Koistinaho, M. PY - 2008 DA - 2008// TI - Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer’s disease JO - Glia VL - 56 UR - https://doi.org/10.1002/glia.20599 DO - 10.1002/glia.20599 ID - Pihlaja2008 ER - TY - JOUR AU - Ambrosini, E. AU - Remoli, M. E. AU - Giacomini, E. AU - Rosicarelli, B. AU - Serafini, B. AU - Lande, R. PY - 2005 DA - 2005// TI - Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions JO - J Neuropathol Exp Neurol VL - 64 UR - https://doi.org/10.1097/01.jnen.0000173893.01929.fc DO - 10.1097/01.jnen.0000173893.01929.fc ID - Ambrosini2005 ER - TY - JOUR AU - Taxman, D. J. AU - Holley-Guthrie, E. A. AU - Huang, M. T. AU - Moore, C. B. AU - Bergstralh, D. T. AU - Allen, I. C. PY - 2011 DA - 2011// TI - The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M111.221077 DO - 10.1074/jbc.M111.221077 ID - Taxman2011 ER - TY - JOUR AU - Abdelaziz, D. H. AU - Gavrilin, M. A. AU - Akhter, A. AU - Caution, K. AU - Kotrange, S. AU - Khweek, A. A. PY - 2011 DA - 2011// TI - Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages JO - Front Microbiol. VL - 2 UR - https://doi.org/10.3389/fmicb.2011.00018 DO - 10.3389/fmicb.2011.00018 ID - Abdelaziz2011 ER - TY - JOUR AU - Takahashi, H. AU - Tashiro, T. AU - Miyazaki, M. AU - Kobayashi, M. AU - Pollard, R. B. AU - Suzuki, F. PY - 2002 DA - 2002// TI - An essential role of macrophage inflammatory protein 1alpha/CCL3 on the expression of host’s innate immunities against infectious complications JO - J Leukoc Biol VL - 72 ID - Takahashi2002 ER - TY - JOUR AU - Lindell, D. M. AU - Standiford, T. J. AU - Mancuso, P. AU - Leshen, Z. J. AU - Huffnagle, G. B. PY - 2001 DA - 2001// TI - Macrophage inflammatory protein 1alpha/CCL3 is required for clearance of an acute Klebsiella pneumoniae pulmonary infection JO - Infect Immun VL - 69 UR - https://doi.org/10.1128/IAI.69.10.6364-6369.2001 DO - 10.1128/IAI.69.10.6364-6369.2001 ID - Lindell2001 ER -