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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammation

Fig. 7

Gene expression (a, b, and d) and protein (c) levels of tyrosine hydroxylase (TH) in the LC, A1, and A2 brainstem noradrenergic cell groups of wild-type (white square) and transgenic (SHR72) rats (black square) exposed to a single (1 × 2 h) or repeated (7 × 2 h) immobilization stress (IMO). Each sample of TH protein represents a pool of two to three animals (c), values are expressed as arbitrary units (A.U.) calculated as a ratio between TH and GAPDH in a given sample. C control; 6×IMO + 24 h-adapted IMO rats exposed to 6×IMO for 2 h and decapitated 24 h after the last IMO. Each value is the mean ± SEM (n = 5–8; a, b, and d). Statistical significance vs. corresponding wild-type group: *P < 0.05; statistical significance vs. wild-type control group: # P < 0.05

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