Fig. 7From: Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammationGene expression (a, b, and d) and protein (c) levels of tyrosine hydroxylase (TH) in the LC, A1, and A2 brainstem noradrenergic cell groups of wild-type (white square) and transgenic (SHR72) rats (black square) exposed to a single (1 × 2 h) or repeated (7 × 2 h) immobilization stress (IMO). Each sample of TH protein represents a pool of two to three animals (c), values are expressed as arbitrary units (A.U.) calculated as a ratio between TH and GAPDH in a given sample. C control; 6×IMO + 24 h-adapted IMO rats exposed to 6×IMO for 2 h and decapitated 24 h after the last IMO. Each value is the mean ± SEM (n = 5–8; a, b, and d). Statistical significance vs. corresponding wild-type group: *P < 0.05; statistical significance vs. wild-type control group: # P < 0.05Back to article page