Fig. 8

Gene expression of pro-inflammatory factors TNF-α (a), iNOS2 (c), and anti-inflammatory factors IL-10 (b) and TGFβ1 (d) in the LC of wild-type (white square) and transgenic (SHR72) rats (black square) exposed to a single (1 × 2 h) or repeated (7 × 2 h) immobilization stress (IMO). C control; 6×IMO + 24 h-adapted IMO rats exposed to 6×IMO for 2 h and decapitated 24 h after the last IMO. Each value is the mean ± SEM (n = 5–8). Statistical significance vs. corresponding wild-type group: *P < 0.05; **P < 0.01; statistical significance vs. wild-type control group: ^# P < 0.05, ^## P < 0.01