Table 2 Ki67- and caspase-3-positive cells
Control | 1-day fluconazole | 3-day C. albicans | 3-day C. albicans and fluconazole | 5-day C. albicans and fluconazole | |
|---|---|---|---|---|---|
Ki67 + cells/mm2 | |||||
White matter | 11.2 (7.2) | 41.6 (38.7) | 21.9 (16.4) | 54.7 (71.0) | 56.0 (31.1)* |
Periventricular white matter | 7.6 (9.1) | 14.4 (11.2) | 17.6 (14.2) | 8.6 (10.7) | 20.9 (18.9) |
Hippocampus | 5.6 (4.2) | 16.8 (13.6) | 22.2 (27.5) | 13.1 (13.0) | 33.4 (27.0)* |
Caspase-3 + cells/mm2 | |||||
White matter | 12.8 (13.6) | 14.1 (11.1) | 23.7 (33.2) | 16.9 (6.8) | 40.2 (22.6)* |
Periventricular white matter | 26.1 (11.4) | 35.4 (24.4) | 93.4 (110.2) | 46.4 (29.1) | 155.1 (22.4)* |
Hippocampus | 364.3 (175.3) | 264.4 (19.6) | 443.2 (198.8) | 313.4 (117.0) | 726.3 (317.9)* |