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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: The expression of the chemokine receptor CCR5 in tick-borne encephalitis

Fig. 7

Concentrations of CCR5 ligands in cerebrospinal fluid of TBEV-infected patients. Concentrations of CCL3, CCL4, and CCL5 in the cerebrospinal fluid of a pilot group of TBE patients on admission to hospital (I, n = 11) and in the early convalescent period after 10–14 days (II, n = 6) measured immunoenzymatically as described in “Methods” and expressed in pg/ml. The detection limit was 10 pg/ml for CCL3, 4 pg/ml for CCL4, and 2 pg/ml for CCL5. Shown are median (horizontal line), quadrilles (box), and minimum and maximum values (whiskers). a Elevated concentration of CCL5, but not CCL3 and CCL4, in comparison with controls with no infectious nor inflammatory pathology (C, n = 5); *significant difference in comparison with C (p << 0.05); **significant difference in comparison with C, p < 0.01; b Concentration of CCL5 in TBE on admission compared to neuroborreliosis (NB, n = 4) and aseptic meningitis (AM, n = 4) patients—no statistically significant difference between the groups, *significantly higher median concentration in comparison with controls

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