Fig. 1
From: Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation
Expression of A2a receptors in autoimmune demyelination. a Expression of A2aR in naïve and active EAE (in C57BL/6 mouse strain) the spinal cord tissue. The protein A2aR has a molecular weight of approximately 42 kDA; the Western blotting band at ~65–70 kDa that we detected has been described for A2aR in the brain tissue before and is probably due to glycosylation [54, 55]. Use of a blocking peptide to the antibody against A2aR demonstrated specificity (see Additional file 1: Figure S1). b Expression of adenosine receptors and adenosine-generating ecto-enzymes in the spinal cord tissue in the course of adoptive transfer EAE (in SJL/J mouse strain). *p < 0.05, **p < 0.01