Fig. 5From: Activation of the NLRP3 inflammasome in lipopolysaccharide-induced mouse fatigue and its relevance to chronic fatigue syndromeEffect of NLRP3 deficiency on behavioural parameters in the CFS model. a Increased locomotor activity in NLRP3 KO mice compared with wild-type mice. b Increased fall-off time in NLRP3 KO mice following LPS/swim challenge compared with wild-type mice in the rota-rod test. *p < 0.05 (independent t test). (n = 8–10 mice per group)Back to article page