TY - JOUR AU - Johnson, V. E. AU - Stewart, W. AU - Smith, D. H. PY - 2010 DA - 2010// TI - Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer’s disease? JO - Nat Rev Neurosci VL - 11 ID - Johnson2010 ER - TY - JOUR AU - Jellinger, K. A. PY - 2004 DA - 2004// TI - Traumatic brain injury as a risk factor for Alzheimer’s disease JO - J Neurol Neurosurg Psychiatry VL - 75 ID - Jellinger2004 ER - TY - STD TI - Stocchetti N, Paterno R, Citerio G, Beretta L, Colombo A: Traumatic brain injury in an aging population. J Neurotrauma. 2012; 29:1119-25. ID - ref3 ER - TY - JOUR AU - Schonberger, M. AU - Ponsford, J. AU - Reutens, D. AU - Beare, R. AU - O'Sullivan, R. PY - 2009 DA - 2009// TI - The Relationship between age, injury severity, and MRI findings after traumatic brain injury JO - J Neurotrauma VL - 26 UR - https://doi.org/10.1089/neu.2009.0939 DO - 10.1089/neu.2009.0939 ID - Schonberger2009 ER - TY - JOUR AU - Himanen, L. AU - Portin, R. AU - Isoniemi, H. AU - Helenius, H. AU - Kurki, T. AU - Tenovuo, O. PY - 2006 DA - 2006// TI - Longitudinal cognitive changes in traumatic brain injury: a 30-year follow-up study JO - Neurology VL - 66 UR - https://doi.org/10.1212/01.wnl.0000194264.60150.d3 DO - 10.1212/01.wnl.0000194264.60150.d3 ID - Himanen2006 ER - TY - JOUR AU - Mushkudiani, N. A. AU - Engel, D. C. AU - Steyerberg, E. W. AU - Butcher, I. AU - Lu, J. AU - Marmarou, A. AU - Slieker, F. AU - McHugh, G. S. AU - Murray, G. D. AU - Maas, A. I. PY - 2007 DA - 2007// TI - Prognostic value of demographic characteristics in traumatic brain injury: results from the IMPACT study JO - J Neurotrauma VL - 24 UR - https://doi.org/10.1089/neu.2006.0028 DO - 10.1089/neu.2006.0028 ID - Mushkudiani2007 ER - TY - JOUR AU - Woodcock, T. AU - Morganti-Kossmann, M. C. PY - 2013 DA - 2013// TI - The role of markers of inflammation in traumatic brain injury JO - Front Neurol VL - 4 UR - https://doi.org/10.3389/fneur.2013.00018 DO - 10.3389/fneur.2013.00018 ID - Woodcock2013 ER - TY - JOUR AU - Giunta, B. AU - Obregon, D. AU - Velisetty, R. AU - Sanberg, P. R. AU - Borlongan, C. V. AU - Tan, J. PY - 2012 DA - 2012// TI - The immunology of traumatic brain injury: a prime target for Alzheimer’s disease prevention JO - J Neuroinflammation VL - 9 UR - https://doi.org/10.1186/1742-2094-9-185 DO - 10.1186/1742-2094-9-185 ID - Giunta2012 ER - TY - JOUR AU - Ziebell, J. M. AU - Morganti-Kossmann, M. C. PY - 2010 DA - 2010// TI - Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury JO - Neurotherapeutics VL - 7 UR - https://doi.org/10.1016/j.nurt.2009.10.016 DO - 10.1016/j.nurt.2009.10.016 ID - Ziebell2010 ER - TY - JOUR AU - Lee, D. C. AU - Ruiz, C. R. AU - Lebson, L. AU - Selenica, M. L. AU - Rizer, J. AU - Hunt, J. B. AU - Rojiani, R. AU - Reid, P. AU - Kammath, S. AU - Nash, K. PY - 2013 DA - 2013// TI - Aging enhances classical activation but mitigates alternative activation in the central nervous system JO - Neurobiol Aging VL - 34 UR - https://doi.org/10.1016/j.neurobiolaging.2012.12.014 DO - 10.1016/j.neurobiolaging.2012.12.014 ID - Lee2013 ER - TY - JOUR AU - Inadera, H. AU - Egashira, K. AU - Takemoto, M. AU - Ouchi, Y. AU - Matsushima, K. PY - 1999 DA - 1999// TI - Increase in circulating levels of monocyte chemoattractant protein-1 with aging JO - J Interferon Cytokine Res VL - 19 UR - https://doi.org/10.1089/107999099313127 DO - 10.1089/107999099313127 ID - Inadera1999 ER - TY - JOUR AU - Saederup, N. AU - Cardona, A. E. AU - Croft, K. AU - Mizutani, M. AU - Cotleur, A. C. AU - Tsou, C. -. L. AU - Ransohoff, R. M. AU - Charo, I. F. PY - 2010 DA - 2010// TI - Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-Red fluorescent protein knock-in mice JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0013693 DO - 10.1371/journal.pone.0013693 ID - Saederup2010 ER - TY - JOUR AU - Morganti, J. M. AU - Jopson, T. D. AU - Liu, S. AU - Riparip, L. K. AU - Guandique, C. K. AU - Gupta, N. AU - Ferguson, A. R. AU - Rosi, S. PY - 2015 DA - 2015// TI - CCR2 antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury JO - J Neurosci VL - 35 UR - https://doi.org/10.1523/JNEUROSCI.2405-14.2015 DO - 10.1523/JNEUROSCI.2405-14.2015 ID - Morganti2015 ER - TY - JOUR AU - Cardona, A. E. AU - Huang, D. AU - Sasse, M. E. AU - Ransohoff, R. M. PY - 2006 DA - 2006// TI - Isolation of murine microglial cells for RNA analysis or flow cytometry JO - Nat Protoc VL - 1 UR - https://doi.org/10.1038/nprot.2006.327 DO - 10.1038/nprot.2006.327 ID - Cardona2006 ER - TY - JOUR AU - Morganti, J. M. AU - Riparip, L. -. K. AU - Rosi, S. PY - 2016 DA - 2016// TI - Call Off the Dog(ma): M1/M2 polarization is concurrent following traumatic brain injury JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0148001 DO - 10.1371/journal.pone.0148001 ID - Morganti2016 ER - TY - JOUR AU - Stefini, R. AU - Catenacci, E. AU - Piva, S. AU - Sozzani, S. AU - Valerio, A. AU - Bergomi, R. AU - Cenzato, M. AU - Mortini, P. AU - Latronico, N. PY - 2008 DA - 2008// TI - Chemokine detection in the cerebral tissue of patients with posttraumatic brain contusions JO - J Neurosurg VL - 108 UR - https://doi.org/10.3171/JNS/2008/108/5/0958 DO - 10.3171/JNS/2008/108/5/0958 ID - Stefini2008 ER - TY - STD TI - Limatola C, Ransohoff RM: Modulating neurotoxicity through CX3CL1/CX3CR1 signaling. Front Cell Neuro 2014; 8:229. ID - ref17 ER - TY - JOUR AU - Bachstetter, A. D. AU - Morganti, J. M. AU - Jernberg, J. AU - Schlunk, A. AU - Mitchell, S. H. AU - Brewster, K. W. AU - Hudson, C. E. AU - Cole, M. J. AU - Harrison, J. K. AU - Bickford, P. C. AU - Gemma, C. PY - 2011 DA - 2011// TI - Fractalkine and CX 3 CR1 regulate hippocampal neurogenesis in adult and aged rats JO - Neurobiol Aging VL - 32 UR - https://doi.org/10.1016/j.neurobiolaging.2009.11.022 DO - 10.1016/j.neurobiolaging.2009.11.022 ID - Bachstetter2011 ER - TY - JOUR AU - Cardona, A. E. AU - Pioro, E. P. AU - Sasse, M. E. AU - Kostenko, V. AU - Cardona, S. M. AU - Dijkstra, I. M. AU - Huang, D. AU - Kidd, G. AU - Dombrowski, S. AU - Dutta, R. PY - 2006 DA - 2006// TI - Control of microglial neurotoxicity by the fractalkine receptor JO - Nat Neurosci VL - 9 UR - https://doi.org/10.1038/nn1715 DO - 10.1038/nn1715 ID - Cardona2006 ER - TY - JOUR AU - Morganti, J. M. AU - Nash, K. R. AU - Grimmig, B. A. AU - Ranjit, S. AU - Small, B. AU - Bickford, P. C. AU - Gemma, C. PY - 2012 DA - 2012// TI - The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson’s disease JO - J Neurosci VL - 32 UR - https://doi.org/10.1523/JNEUROSCI.0539-12.2012 DO - 10.1523/JNEUROSCI.0539-12.2012 ID - Morganti2012 ER - TY - JOUR AU - Hickman, S. E. AU - Kingery, N. D. AU - Ohsumi, T. AU - Borowsky, M. AU - Wang, L. -. c. AU - Means, T. K. AU - Khoury, J. E. PY - 2013 DA - 2013// TI - The microglial sensome revealed by direct RNA sequencing JO - Nat Neurosci VL - 16 UR - https://doi.org/10.1038/nn.3554 DO - 10.1038/nn.3554 ID - Hickman2013 ER - TY - JOUR AU - Kumar, A. AU - Stoica, B. A. AU - Sabirzhanov, B. AU - Burns, M. P. AU - Faden, A. I. AU - Loane, D. J. PY - 2013 DA - 2013// TI - Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states JO - Neurobiol Aging VL - 34 UR - https://doi.org/10.1016/j.neurobiolaging.2012.11.013 DO - 10.1016/j.neurobiolaging.2012.11.013 ID - Kumar2013 ER - TY - JOUR AU - Yamasaki, R. AU - Lu, H. AU - Butovsky, O. AU - Ohno, N. AU - Rietsch, A. M. AU - Cialic, R. AU - Wu, P. M. AU - Doykan, C. E. AU - Lin, J. AU - Cotleur, A. C. PY - 2014 DA - 2014// TI - Differential roles of microglia and monocytes in the inflamed central nervous system JO - J Exp Med VL - 211 UR - https://doi.org/10.1084/jem.20132477 DO - 10.1084/jem.20132477 ID - Yamasaki2014 ER - TY - JOUR AU - Khoury, J. AU - Toft, M. AU - Hickman, S. E. AU - Means, T. K. AU - Terada, K. AU - Geula, C. AU - Luster, A. D. PY - 2007 DA - 2007// TI - Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease JO - Nat Med VL - 13 UR - https://doi.org/10.1038/nm1555 DO - 10.1038/nm1555 ID - Khoury2007 ER - TY - JOUR AU - Mildner, A. AU - Mack, M. AU - Schmidt, H. AU - Bruck, W. AU - Djukic, M. AU - Zabel, M. D. AU - Hille, A. AU - Priller, J. AU - Prinz, M. PY - 2009 DA - 2009// TI - CCR2+ Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system JO - Brain VL - 132 UR - https://doi.org/10.1093/brain/awp144 DO - 10.1093/brain/awp144 ID - Mildner2009 ER - TY - JOUR AU - Shechter, R. AU - Miller, O. AU - Yovel, G. AU - Rosenzweig, N. AU - London, A. AU - Ruckh, J. AU - Kim, K. W. AU - Klein, E. AU - Kalchenko, V. AU - Bendel, P. PY - 2013 DA - 2013// TI - Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus JO - Immunity VL - 38 UR - https://doi.org/10.1016/j.immuni.2013.02.012 DO - 10.1016/j.immuni.2013.02.012 ID - Shechter2013 ER - TY - JOUR AU - Donnelly, D. J. AU - Longbrake, E. E. AU - Shawler, T. M. AU - Kigerl, K. A. AU - Lai, W. AU - Tovar, C. A. AU - Ransohoff, R. M. AU - Popovich, P. G. PY - 2011 DA - 2011// TI - Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages JO - J Neurosci VL - 31 UR - https://doi.org/10.1523/JNEUROSCI.2114-11.2011 DO - 10.1523/JNEUROSCI.2114-11.2011 ID - Donnelly2011 ER - TY - JOUR AU - Auffray, C. AU - Fogg, D. AU - Garfa, M. AU - Elain, G. AU - Join-Lambert, O. AU - Kayal, S. AU - Sarnacki, S. AU - Cumano, A. AU - Lauvau, G. AU - Geissmann, F. PY - 2007 DA - 2007// TI - Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior JO - Science VL - 317 UR - https://doi.org/10.1126/science.1142883 DO - 10.1126/science.1142883 ID - Auffray2007 ER - TY - JOUR AU - Gyoneva, S. AU - Ransohoff, R. M. PY - 2015 DA - 2015// TI - Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell-cell communication by chemokines JO - Trends Pharmacol Sci VL - 36 UR - https://doi.org/10.1016/j.tips.2015.04.003 DO - 10.1016/j.tips.2015.04.003 ID - Gyoneva2015 ER - TY - JOUR AU - Hernandez-Ontiveros, D. G. AU - Tajiri, N. AU - Acosta, S. AU - Giunta, B. AU - Tan, J. AU - Borlongan, C. V. PY - 2013 DA - 2013// TI - Microglia activation as a biomarker for traumatic brain injury JO - Front Neurol VL - 4 UR - https://doi.org/10.3389/fneur.2013.00030 DO - 10.3389/fneur.2013.00030 ID - Hernandez-Ontiveros2013 ER - TY - JOUR AU - Wynn, T. A. AU - Chawla, A. AU - Pollard, J. W. PY - 2013 DA - 2013// TI - Macrophage biology in development, homeostasis and disease JO - Nature VL - 496 UR - https://doi.org/10.1038/nature12034 DO - 10.1038/nature12034 ID - Wynn2013 ER - TY - JOUR AU - Norden, D. M. AU - Muccigrosso, M. M. AU - Godbout, J. P. PY - 2015 DA - 2015// TI - Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease JO - Neuropharmacology VL - 96 UR - https://doi.org/10.1016/j.neuropharm.2014.10.028 DO - 10.1016/j.neuropharm.2014.10.028 ID - Norden2015 ER - TY - JOUR AU - Norden, D. M. AU - Godbout, J. P. PY - 2013 DA - 2013// TI - Review: microglia of the aged brain: primed to be activated and resistant to regulation JO - Neuropathol Appl Neurobiol VL - 39 UR - https://doi.org/10.1111/j.1365-2990.2012.01306.x DO - 10.1111/j.1365-2990.2012.01306.x ID - Norden2013 ER - TY - JOUR AU - Deshmane, S. L. AU - Kremlev, S. AU - Amini, S. AU - Sawaya, B. E. PY - 2009 DA - 2009// TI - Monocyte chemoattractant protein-1 (MCP-1): an overview JO - J Interferon Cytokine Res VL - 29 UR - https://doi.org/10.1089/jir.2008.0027 DO - 10.1089/jir.2008.0027 ID - Deshmane2009 ER - TY - JOUR AU - Takahashi, M. AU - Galligan, C. AU - Tessarollo, L. AU - Yoshimura, T. PY - 2009 DA - 2009// TI - Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A JO - J Immunol VL - 183 UR - https://doi.org/10.4049/jimmunol.0802812 DO - 10.4049/jimmunol.0802812 ID - Takahashi2009 ER - TY - STD TI - Mueller A, Kelly E, Strange PG. Pathways for internalization and recycling of the chemokine receptor CCR5. Blood .2002; 99:785–91. ID - ref36 ER - TY - JOUR AU - Blanpain, C. AU - Migeotte, I. AU - Lee, B. AU - Vakili, J. AU - Doranz, B. J. AU - Govaerts, C. AU - Vassart, G. AU - Doms, R. W. AU - Parmentier, M. PY - 1999 DA - 1999// TI - CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist JO - Blood VL - 94 ID - Blanpain1999 ER - TY - JOUR AU - Balboa, L. AU - Romero, M. M. AU - Basile, J. I. AU - Sabio y Garcia, C. A. AU - Schierloh, P. AU - Yokobori, N. AU - Geffner, L. AU - Musella, R. M. AU - Castagnino, J. AU - Abbate, E. PY - 2011 DA - 2011// TI - Paradoxical role of CD16+ CCR2+ CCR5+ monocytes in tuberculosis: efficient APC in pleural effusion but also mark disease severity in blood JO - J Leukoc Biol VL - 90 UR - https://doi.org/10.1189/jlb.1010577 DO - 10.1189/jlb.1010577 ID - Balboa2011 ER - TY - JOUR AU - Wu, D. C. AU - Teismann, P. AU - Tieu, K. AU - Vila, M. AU - Jackson-Lewis, V. AU - Ischiropoulos, H. AU - Przedborski, S. PY - 2003 DA - 2003// TI - NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease JO - Proc Natl Acad Sci U S A VL - 100 UR - https://doi.org/10.1073/pnas.0937239100 DO - 10.1073/pnas.0937239100 ID - Wu2003 ER - TY - JOUR AU - Hernandes, M. S. AU - Britto, L. R. PY - 2012 DA - 2012// TI - NADPH oxidase and neurodegeneration JO - Curr Neuropharmacol VL - 10 UR - https://doi.org/10.2174/1570159X11209040321 DO - 10.2174/1570159X11209040321 ID - Hernandes2012 ER - TY - JOUR AU - Block, M. L. AU - Zecca, L. AU - Hong, J. S. PY - 2007 DA - 2007// TI - Microglia-mediated neurotoxicity: uncovering the molecular mechanisms JO - Nat Rev Neurosci VL - 8 UR - https://doi.org/10.1038/nrn2038 DO - 10.1038/nrn2038 ID - Block2007 ER - TY - JOUR AU - Zhang, Q. G. AU - Laird, M. D. AU - Han, D. AU - Nguyen, K. AU - Scott, E. AU - Dong, Y. AU - Dhandapani, K. M. AU - Brann, D. W. PY - 2012 DA - 2012// TI - Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0034504 DO - 10.1371/journal.pone.0034504 ID - Zhang2012 ER - TY - JOUR AU - Loane, D. J. AU - Stoica, B. A. AU - Byrnes, K. R. AU - Jeong, W. AU - Faden, A. I. PY - 2013 DA - 2013// TI - Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury JO - J Neurotrauma VL - 30 UR - https://doi.org/10.1089/neu.2012.2589 DO - 10.1089/neu.2012.2589 ID - Loane2013 ER -