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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

Fig. 1

Normalized probe dosage quality control of complement C4A (a),C4B (b), and total C4 (c) in three independent studies. Distribution of unrounded MLPA-based dosage estimates for 2645 individuals from three studies (AUS, WUE, and MUE/TUE) are shown. Distinct peaks corresponding to integer copy numbers are demonstrated for C4A, C4B, and total C4. There is no obvious discrepancy in the distribution of the normalized dosages between studies

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