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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK

Fig. 3

Resveratrol inhibits the activation of microglia and astrocytes in rat STN. a, b Representative western blot bands and a data summary (n = 4 each group) of the expression of GFAP and IBA-1, which are markers of astrocytes and microglia, respectively. GFAP and IBA-1 expression were enhanced in the STN of the CCI rats, whereas resveratrol (400 mg/kg, p.o.) downregulated the expression of both markers. *P < 0.05 and **P < 0.01 versus control; and # P < 0.05 and ## P < 0.01 versus the CCI group

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