Fig. 4

Two distinct Ido1 transcripts are expressed by hippocampal slice cultures, with IFNγ being a strong inducer of Ido1 expression and synergistic with corticosteroids. OHSCs were treated with IFNγ, LPS, and pI:C ± Dex, Cort, or Aldo. Expression levels of two Ido1 transcripts (a, c, e: Ido1-FL; b, d, f: Ido1-v1) are relative to control samples normalized to 1.0. *p ≤ 0.05 for the main effect of an inflammatory mediator, ^ϕ p ≤ 0.05 for the main effect of either Dex, Cort, or Aldo; ^δ p ≤ 0.05 post hoc analysis for an interaction effect for Dex, Cort, or Aldo within inflammatory mediator