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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

Fig. 2

Microglia-enriched culture produced both ROS and NO in response to LPS. Representative photographs showing only Iba1-positive (green) cells in the microglial culture. Scale bar, 50 μm (a). After Ara-C/LME-treatment, Iba1-positive cells disappeared. Scale bar, 50 μm (b). LPS induced both ROS (c ROS ) and NO (d NO) production. The rate of ROS/NO production was expressed as percent increase in the fluorescent signal at 60 min compared with that at 0 min. Values are the means ± SD of four wells. ***P < 0.001 versus control (grouped t test)

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