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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

Fig. 9

The effects of sulforaphane (SL). SL, a potent activator of Nrf2, increased GSH content (a GSH) and eliminated LPS-induced increases in ROS and NO. The rate of ROS production (b ROS) and NO production (c NO) in untreated microglia-containing astroglia that had been pretreated with DMSO (open columns) or sulforaphane (10 μmol/L, hatched columns). Values are means ± SD of six wells. ***P < 0.001 versus controls (grouped t test)

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