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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain

Fig. 4

P2RX7 mRNA expression is exclusively increased in patients with neuropathic pain. To confirm the flow cytometric observations with elevated P2X7R protein expression, predominantly on CD4+ cells and only in NeP, we determined the relative P2RX7 mRNA expression of CD4+ cells by qPCR. Affirmatively, increased mRNA levels were consistent with the flow cytometric analyses and exclusively elevated in patients with NeP. (p = 0.038). *p < 0.05. Data are presented as mean ± SD, n = 19, *p < 0.05 in one-way ANOVA with multiple comparisons versus healthy volunteers (Holm-Sidak method)

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