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Table 2 Patients characteristics

From: Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain

 

Healthy

CLBP

NeP

Numbers

19

19

19

Age (years)

40 ± 11

47 ± 13

58 ± 13*

Female (%)

58 %

79 %

68 %

BMI (kg/m2)

23.6 ± 2.9

23.9 ± 3.1

24.6 ± 3.8

Duration of pain (years)

0.0 ± 0.0

5.9 ± 4.2*

4.5 ± 2.8*

NRS (rest)

0.0 ± 0.0

3.5 ± 2.2*

5.1 ± 2.2*

NRS (motion)

0.0 ± 0.0

4.4 ± 2.1*

6.9 ± 2.1*

KAB

1.7 ± 0.7

3.4 ± 0.9*

3.3 ± 0.9*

CES-D

2.4 ± 2.2

21.8 ± 7.3*

21.0 ± 9.6*

  1. Patients with either CLBP or NeP significantly differed from healthy volunteers in terms of duration of pain, NRS, KAB, and CES-D. However, no significant differences were detected between CLBP and NeP patients for any of the parameters. Data are presented as mean ± SD, n = 19, *p < 0.05 versus healthy in paired Student’s t test (NeP) and Mann-Whitney Rank Sum Test (CLBP)
  2. BMI body mass index; NRS (rest/motion) numeric rating scale (0–10) of pain, 0: “no pain,” 10: “worst pain imaginable,” KAB questionnaire for self-perceived stress ranging from 1 (no stress) to 6 (max. stress), CES-D center for epidemiologic studies depression scale, CLBP chronic low back pain, NeP neuropathic pain (symmetrical polyneuropathy, peripheral mononeuropathy, postherpetic neuralgia, orofacial pain)