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Table 2 Patients characteristics

From: Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain

  Healthy CLBP NeP
Numbers 19 19 19
Age (years) 40 ± 11 47 ± 13 58 ± 13*
Female (%) 58 % 79 % 68 %
BMI (kg/m2) 23.6 ± 2.9 23.9 ± 3.1 24.6 ± 3.8
Duration of pain (years) 0.0 ± 0.0 5.9 ± 4.2* 4.5 ± 2.8*
NRS (rest) 0.0 ± 0.0 3.5 ± 2.2* 5.1 ± 2.2*
NRS (motion) 0.0 ± 0.0 4.4 ± 2.1* 6.9 ± 2.1*
KAB 1.7 ± 0.7 3.4 ± 0.9* 3.3 ± 0.9*
CES-D 2.4 ± 2.2 21.8 ± 7.3* 21.0 ± 9.6*
  1. Patients with either CLBP or NeP significantly differed from healthy volunteers in terms of duration of pain, NRS, KAB, and CES-D. However, no significant differences were detected between CLBP and NeP patients for any of the parameters. Data are presented as mean ± SD, n = 19, *p < 0.05 versus healthy in paired Student’s t test (NeP) and Mann-Whitney Rank Sum Test (CLBP)
  2. BMI body mass index; NRS (rest/motion) numeric rating scale (0–10) of pain, 0: “no pain,” 10: “worst pain imaginable,” KAB questionnaire for self-perceived stress ranging from 1 (no stress) to 6 (max. stress), CES-D center for epidemiologic studies depression scale, CLBP chronic low back pain, NeP neuropathic pain (symmetrical polyneuropathy, peripheral mononeuropathy, postherpetic neuralgia, orofacial pain)