Fig. 7
From: Induction of the type I interferon response in neurological forms of Gaucher disease
Gene changes in LSDs. Upper panel Venn diagram of differentially-expressed genes in spinal cord of Sandhoff disease, brain of NPC1 disease, and the VPM/VPL of nGD. Lower panel Venn diagram of differentially expressed genes related to the type I IFN pathway to up-regulated genes in other diseases. The enrichment IFN signaling lists were obtained from GSEA (REACTOME_INTERFERON_SIGNALING). Overlapping regions were drawn to scale and the number of shared and unique genes listed. Overlap was visualized using BioVenn